ImageNest RIP and Epson Advanced Black and White Mode: Epson’s advanced black and white mode functions without any ICC color management so any output (printer class) profile should not be applied. Clicking on the "Epson Color Controls" will allow the Advanced Black and White to work properly. Epson’s Advanced black and white mode will not work if "ColorSync" is selected as the ColorSync controls will try to apply an ICC profile which interferes with Epson’s Advanced Black and White mode which is a non-ICC process.
